metadata: {"type": "project", "title": "overlake.bio", "logoImg": "bafkreih7krpdycgargvkz7zedlvp7kdhif326bqlyqmlturh3yr5ylhpxq", "website": "https://overlake.bio/", "bannerImg": "bafkreibwbu4euofn5kquxek4xgm7jvbbsrzwerx2vmkaapxjgxlzttymhm", "createdAt": 1723083774646, "credentials": {"twitter": {"type": ["VerifiableCredential"], "proof": {"jws": "eyJhbGciOiJFZERTQSIsImNyaXQiOlsiYjY0Il0sImI2NCI6ZmFsc2V9..7keO3gOiFQeRFtzCkdBBvl1bGm72xGTQ9mhUhbprumsTbMN797fbyM8ohknpnpjXCF6483wIWAGykpJd_YYYBw", "type": "Ed25519Signature2018", "created": "2024-08-08T02:16:20.824Z", "proofPurpose": "assertionMethod", "verificationMethod": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC#z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC"}, "issuer": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC", "@context": ["https://www.w3.org/2018/credentials/v1"], "issuanceDate": "2024-08-08T02:16:20.824Z", "expirationDate": "2024-11-06T02:16:20.824Z", "credentialSubject": {"id": "did:pkh:eip155:1:0x59041d70deAEfe849A48E77e0b273DdD072eA9e4", "hash": "v0.0.0:Q14TlWbmR7/a+dCouG1C64GJ3DWo2N4CN+sjmeHQgPo=", "@context": [{"hash": "https://schema.org/Text", "provider": "https://schema.org/Text"}], "provider": "ClearTextTwitter#overlake_bio"}}}, "description": "[**overlake.bio**](https://overlake.bio/) is an end-to-end DeSci framework comprising a collection of [projects](https://overlake.bio/rakhan/projects-0b1edcacb77e4c93a1b8ad8df47c161d) aimed at promoting human longevity:\n\n**1|** Novel insights into translation fidelity in aging: [**Glycation of ribosomes as a driver of proteostasis loss**](https://overlake.bio/rakhan/Glycation-of-ribosomes-as-a-driver-of-proteostasis-loss-d8971d87778846349d8f4fc29a91a30b)\n\n**2|** Engineered biologics to alleviate the glycation load: [**Advanced glycation end product (AGE)-degrading enzymes**](https://overlake.bio/rakhan/Advanced-glycation-end-product-AGE-degrading-enzymes-ce317852187b4639b5e5debe42b62290)\n\n**3|** A knowledgebase of time-resolved matrisome signatures extracted from public proteomic datasets: [**The Extracellular Matrix Aging Atlas**](https://overlake.bio/rakhan/Extracellular-matrix-aging-atlas-10e0f2ecd2f545afad43fd971cce5be7)\n\n**4|** Customizing human genetics to improve resilience and adaptability for thriving in space exploration and extraterrestrial habitats: [**Spacefarer Phenome**](https://overlake.bio/rakhan/Spacefarer-phenome-6df641ad372c4ac5a64b8a666d30a179)\n\n[**VIDEO**](https://www.loom.com/share/492912664ed1495d97b4c1c33a22b3b4?sid=5fc33f9b-ab8f-4a48-9b5b-df23c1174557) \\[2 min\\]", "logoImgData": {}, "bannerImgData": {}, "projectTwitter": "overlake_bio"}
name: overlake.bio